Development and Evaluation of Cetirizine HCl Taste-Masked Oral Disintegrating Tablets

taste-masked fast disintegrating tablets of prednisolone for oral delivery

Design and evaluation of taste masked dextromethorphan hydrobromide oral disintegrating tablets.

The present study is aimed to develop dextromethorphan hydrobromide (DXM) oral disintegrating tablets (ODT) with acceptable palatability to help patients of all age groups. The bitter taste of the drug was masked by binding the drug to ion exchange resin. The effect of the particle size of resin on drug loading was studied. In vitro and in vivo disintegration time and in vitro drug release stud...

Development and optimization of taste-masked orally disintegrating tablets (ODTs) of clindamycin hydrochloride.

The purpose of this research was to develop an orally disintegrating tablet (ODT) dosage form containing taste-masked beads of clindamycin HCl. Several formulation strategies were evaluated and a taste-masked ODT of clindamycin HCl was prepared without the use of a waxy cushioning agent. Clindamycin HCl (ca. 46% w/w) was coated onto microcrystalline cellulose beads (Cellets® 200) followed by th...

Preparation and evaluation of taste-masked donepezil hydrochloride orally disintegrating tablets.

The purpose of this research was to prepare and evaluate a non-bitter donepezil hydrochloride (DH) orally disintegrating tablet (ODT) for enhanced patient compliance. Taste masking was done by preparing microspheres with different ratios of drug and Eudragit EPO using spray drying method. The entrapment of the drug into microspheres was confirmed by scanning electron microscope (SEM) and X-ray ...

Formulation, In vitro and In vivo Evaluation of Taste Masked Rasagiline Orally Fast Disintegrating Tablets (ODTS)

Orally disintegrating tablets (ODTs) have become a rapidly growing area in the pharmaceutical industry during the last decade. Drugs exhibit the advantage of good absorption from the oral mucosa or intending for immediate pharmacological action can be formulated as ODT dosage forms. Rasagiline, a second generation, selective, irreversible inhibitor of mono amine oxidase type B drug, is primaril...